Does CBD oil have unwanted side effects? As you probably know, CBD oil is made from hemp. And as with any natural product, CBD oil will have different effects on different people. But CBD is non-toxic. And part of being non-toxic is being non-intoxicating. You could eat a brick of pure CBD and not get high or have any long-term consequences. However, depending on your needs, some of the effects of CBD oil might be unwanted. So, what, exactly, are the side effects of CBD oil?